Hyperactive mTORC1/4EBP1 Signaling Dysregulates Proteostasis and Accelerates Cardiac Aging.
Weronika Zarzycka, Kamil Aleksander Kobak, Catherine J. King, Frederick F. Peelor, Benjamin F. Miller, Ying Ann Chiao
This study shows that hyperactive mTORC1/4EBP1 signaling accelerates cardiac aging by dysregulating proteostasis in mice.
GeroScience · Oct 8, 2024Peer-reviewedMolecular Biology