The rapid developmental rise of somatic inhibition disengages hippocampal dynamics from self-motion
Robin F. Dard, Erwan Leprince, Julien Denis, Shrisha Rao Balappa, Dmitrii Suchkov, Richard Boyce, Catherine Lopez, Marie Giorgi-Kurz, Tom Szwagier, Théo Dumont, Hervé Rouault, Marat Minlebaev, Agnès Baude, Rosa Cossart, Michel A. Picardo
The paper shows that in mouse hippocampus, CA1 pyramidal cells switch from being activated to inhibited by self-motion around postnatal day 7, linked to increased local GABAergic innervation.
eLife · Jul 20, 2022Peer-reviewedNeuroscience