Combating Chagas Disease Through Inhibition of Tiam1, a Rho GTPase Guanine Nucleotide Exchange Factor
Chirag Krishna, Li Xie, Celine DerMarderossian, Philip E. Bourne
The paper investigates the potential of Posaconazole to inhibit Tiam1 and disrupt Rho GTPase activity, offering a new approach for treating Chagas Disease.
bioRxiv · Feb 18, 2016 · PreprintBioinformatics