THE CREATION OF A NEGATIVE SLOPE CONDUCTANCE REGION BY THE ACTIVATION OF THE PERSISTENT SODIUM CURRENT PROLONGS NEAR-THRESHOLD SYNAPTIC POTENTIALS
Cesar C. Ceballos, Antonio C. Roque, Ricardo M. Leão
This paper demonstrates that the persistent sodium current (INaP) increases input resistance and membrane time constant near the firing threshold through negative slope conductance, enhancing excitability.
bioRxiv · Nov 1, 2016 · PreprintBiophysics