Aging and neurodegeneration are associated with increased mutations in single human neurons
Michael A. Lodato, Rachel E. Rodin, Craig L. Bohrson, Michael E. Coulter, Alison R. Barton, Min‐Seok Kwon, Maxwell A. Sherman, Carl M. Vitzthum, Lovelace J. Luquette, Chandri Yandava, Pengwei Yang, Thomas W. Chittenden, Nicole E. Hatem, Steven C. Ryu, Mollie B. Woodworth, , Christopher A. Walsh
The paper identifies age-related accumulation of somatic mutations in human neurons and links them to neurodegenerative diseases.
Science · Dec 7, 2017Peer-reviewedGenomics