Circadian-Modulated Thresholds as a Mechanistic Basis for Sleep-Wake Transitions, Recovery, and Sleepiness
Chenggui Yao, Junjie Jiang, Changgui Gu, Jianwei Shuai, Dongping Yang
This paper develops a computational model that explains sleep-wake transitions and sleepiness through circadian-modulated thresholds, showing how circadian and homeostatic drives interact dynamically.
bioRxiv · Feb 6, 2026 · PreprintNeuroscience