Single-cell analysis identifies distinct CD4+ T cells associated with the pathobiology of pediatric obesity-related asthma
David A. Thompson, Yvonne B. Wabara, Sarai Duran, Anna Reichenbach, Laura Chen, Kayla Collado, Changsuek Yon, John M. Greally, Deepa Rastogi
The paper identifies distinct CD4+ T cell subtypes in obese asthma linked to CDC42 upregulation, Th1 inflammation, and steroid resistance.
Scientific Reports · Feb 25, 2025Peer-reviewedImmunology