Hierarchical Interplay between H3K27ac and H3K4me3 in Transcriptional Regulation
Chenwei Zhou, Chanjuan Dong, Weiye Zhao, Fu‐Sen Liang
This study develops a CRISPR/dCas9-based system to modulate H3K27ac and H3K4me3 independently and shows their distinct roles in transcriptional regulation at different stages.
Nature Communications · Jun 22, 2026Peer-reviewedGenomics