Estimating the respective contributions of human and viral genetic variation to HIV control
Istvan Bartha, Paul J McLaren, Chanson Brumme, Richard Harrigan, Amalio Telenti, Jacques Fellay
The paper estimates that viral genetic factors explain 29% and human factors 8.4% of variation in HIV-1 set point viral load, with a total heritability of 30%.
PLOS Computational Biology · Feb 9, 2017Peer-reviewedGenetics