Author

Richard Harrigan

University of British Columbia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:virus· 3 Approach:experimental assay· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Organism:E. coli· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Amalio TelentiiD· 1 shared Andrew D. SmithiD· 1 shared Arthur WickenhageniD· 1 shared Cecile L. TremblayiD· 1 shared Chanson Brumme· 1 shared David Stoddart· 1 shared DE KaufmanniD· 1 shared Floriane PointiD· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperGenetics

Amalio TelentiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Impact of cobas PCR Media Freezing on SARS-CoV-2 Viral RNA Integrity and Whole Genome Sequencing Analyses

Patrick Benoit, Floriane Point, Simon Gagnon, DE Kaufmann, Cecile L. Tremblay, Richard Harrigan, Isabelle Hardy, François Coutlée, Simon Grandjean Lapierre

This study evaluates the impact of freezing cobas PCR Media on SARS-CoV-2 RNA integrity and whole genome sequencing results, finding no significant negative effects.

Diagnostic Microbiology and Infectious Disease · Aug 20, 2021Peer-reviewedMolecular Biology

Improvements to the ARTIC multiplex PCR method for SARS-CoV-2 genome sequencing using nanopore

John R. Tyson, Phillip L. James, David Stoddart, Natalie Sparks, Arthur Wickenhagen, Grant Hall, Ji Hyun Choi, Hope R. Lapointe, Kimia Kamelian, Andrew D. Smith, Natalie Prystajecky, Ian Goodfellow, Sam J. Wilson, Richard Harrigan, Terrance P. Snutch, , Joshua Quick

V3 primer pools with 22 extra alternates improve coverage; revised library preps raise double-barcode demultiplexing from 42.15% to 74.5%, cut misassignment 35x and bring reagent cost near £10 per sample.

bioRxiv · Sep 4, 2020 · PreprintGenomics✦ In-depth digest

Estimating the respective contributions of human and viral genetic variation to HIV control

Istvan Bartha, Paul J McLaren, Chanson Brumme, Richard Harrigan, Amalio Telenti, Jacques Fellay

The paper estimates that viral genetic factors explain 29% and human factors 8.4% of variation in HIV-1 set point viral load, with a total heritability of 30%.

PLOS Computational Biology · Feb 9, 2017Peer-reviewedGenetics