Regulation of PDGF-BB Signaling in Placental Pericytes by Soluble PDGFRβ Isoforms: Implications for Fetoplacental Vascular Development
Audra Barnes, Emily C. Duggan, Reese Dunkenberger, Chloe Lessard, Christopher Cosma, Chase Steele, Sarah V Taylor, Megan D. Whitham, Allison R. Durica, John C. Chappell
This study identifies progressive pericyte recruitment to placental capillaries and shows that soluble PDGFRβ isoforms modulate PDGF-BB signaling in response to hypoxia.
bioRxiv · Mar 27, 2026 · PreprintDevelopmental Biology