Identification of Multi-landscape and Cell Interactions in the Tumor Microenvironment through High-Coverage Single-Cell Sequencing
Wenlong Zhong, Ligang Wang, Chengjunyu Zhang, Tonglei Guo, Lihua Zhao, Daqin Wu, Fei Xie, Xiaodong Wang, Xiuxin Li, Fangxiao Wang, Minghui Li, Weiyue Gu, Tianxin Lin, Xu Chen
The paper introduces a high-coverage scRNA-seq platform called Chigene that detects gene expression, mutations, and splicing at the single-cell level, revealing novel mutations and cell interactions in urothelial carcinoma.
Small Methods · May 5, 2025Peer-reviewedGenomics