Temporal and spatial dynamics of Plasmodium falciparum clonal lineages in Guyana
Mathieu Vanhove, Philipp Schwabl, Collette Clementson, Angela M. Early, Margaret Laws, Frank Anthony, Célia Florimond, Luana Mathieu, Kashana James, Cheyenne Knox, Narine Singh, Caroline O. Buckee, Lise Musset, Horace Cox, Reza A. Niles-Robin, Daniel E. Neafsey
The paper analyzes clonal dynamics of Plasmodium falciparum in Guyana using whole genome sequencing, finding that stochastic factors drive clonality rather than deterministic selection for drug resistance mutations.
PLoS Pathogens · Jun 13, 2024Peer-reviewedGenomics