Angela M. Early

The paper analyzes parasite genotypes in sympatric mosquito species to show divergent selection on Plasmodium falciparum mediated by different vectors.

The paper argues that low diversity in pathogen proteins does not necessarily indicate evolutionary constraint and introduces a tool to explore diversity and divergence in Plasmodium falciparum proteins.

The paper introduces a standardized format for storing phased targeted sequencing data and provides tools to create and manipulate this format.

This study analyzes whole genomes of 1094 Anopheles darlingi mosquitoes from six South American countries, revealing geographic structure, genetic diversity, and selection signals on cytochrome P450 genes.

The paper examines how evolutionary forces differ across life stages of Plasmodium falciparum, finding reduced selection efficacy in genes expressed in sporozoites.

The paper analyzes temporal changes in haplotypic and allelic diversity in Plasmodium falciparum to understand how drug selection pressures shape genetic adaptation.

The paper analyzes clonal dynamics of Plasmodium falciparum in Guyana using whole genome sequencing, finding that stochastic factors drive clonality rather than deterministic selection for drug resistance mutations.

The paper performs high-resolution RNA-seq time course analysis of Drosophila immune response to Imd stimulation, identifying gene expression dynamics and trade-offs with metabolic processes.