Batch effects and the effective design of single-cell gene expression studies
Po-Yuan Tung, John D Blischak, Chiaowen Hsiao, David A Knowles, Jonathan E Burnett, Jonathan K Pritchard, Yoav Gilad
This study identifies genotype as the major source of variation in scRNA-seq data and highlights technical replicate variation, suggesting a framework for effective study design.
Scientific Reports · Jan 3, 2017Peer-reviewedGenomics