A single-gene-based AI model to identify core and context-specific essential genes by biological interpretation from pooled genome-wide CRISPR and omics data
Chih-Yuan Chou, Jung-Yu Lee, Chia‐Hwa Lee, Jinn‐Moon Yang
The paper develops an AI model to identify core and context-specific essential genes using CRISPR and omics data, finding 3,213 pan-cancer CEGs with 60% overlap to prior studies.
bioRxiv · Nov 3, 2024 · PreprintBioinformatics