Learning the Language of Antibody Hypervariability
Rohit Singh, Chiho Im, Yu Qiu, Brian C. Mackness, Abhinav Gupta, Taylor Joren, Samuel Sledzieski, Lena Erlach, Maria Wendt, Yves Fomekong‐Nanfack, Bryan D. Bryson, Bonnie Berger
This paper introduces AbMAP, a transfer learning framework for antibody sequence analysis, showing it can predict structure, binding, and paratope with high accuracy and enable antibody optimization.
Proceedings of the National Academy of Sciences · Dec 30, 2024Peer-reviewedBioinformatics