Transcriptomic analysis of dystonia-associated genes reveals functional convergence within specific cell types and shared neurobiology with psychiatric disorders
Niccolò Emanuele Mencacci, Regina Hertfelder Reynolds, Sonia García-Ruiz, Jana Vandrovcová, Paola Forabosco, Álvaro Sánchez‐Ferrer, Viola Volpato, Juan Antonio Botía, Karishma D’Sa, Sebastian Guelfi, John Hardy, Chris-Ann Mackenzie, Adaikalavan Ramasamy, Mina Ryten, Colin Smith, , Caleb Webber
This study identifies cell-type-specific expression of dystonia-associated genes and links them to shared genetic and biological mechanisms with psychiatric disorders.
Brain · Jun 17, 2020Peer-reviewedGenetics