A complex balance: PLETHORA - JANUS ratiometry explains the PLETHORA dosage regeneration paradox
Monica L. García‐Gómez, Mabel Maria Mathew, Srijan Das, Chris Roelofsen, Viola Willemsen, Kalika Prasad, Kirsten ten Tusscher
The paper explains how the balance between PLETHORA protein complexes and unbound PLETHORA determines regenerative competence in Arabidopsis roots, revealing a ratiometric mechanism for transcription factor dosage.
bioRxiv · Oct 16, 2026 · PreprintDevelopmental Biology