Sequencing depth overcomes extraction bias: repurposing human WGS data for salivary microbiome profiling
Lourdes Velo‐Suárez, Anthony F. Herzig, Ozvan Bocher, Gaëlle Le Folgoc, Liana Le Roux, Christelle Delmas, Marie Zins, Jean‐François Deleuze, Geneviève Héry-Arnaud, Emmanuelle Génin
This paper shows that repurposing existing human WGS saliva data for microbiome profiling is feasible, with sequencing depth overcoming extraction bias and enabling robust oral microbiome analysis.
bioRxiv · Apr 1, 2026 · PreprintGenomics