Marie Zins

Sequencing depth overcomes extraction bias: repurposing human WGS data for salivary microbiome profiling

This paper shows that repurposing existing human WGS saliva data for microbiome profiling is feasible, with sequencing depth overcoming extraction bias and enabling robust oral microbiome analysis.

SURFBAT: a surrogate family-based association test building on large imputation reference panels

SURFBAT approximates transmission-disequilibrium tests using imputed haplotypes to detect genotype-phenotype associations while being robust to population stratification.

Can imputation in a European country be improved by local reference panels? The example of France

The paper evaluates whether using a local reference panel improves imputation accuracy in French individuals compared to a public reference panel, showing benefits of combining both approaches.

Genetic population structure across Brittany and the downstream Loire basin provides new insights on the demographic history of Western Europe

The paper analyzes genetic structure in Brittany and the Loire basin to understand Western Europe's demographic history, finding increased population differentiation linked to steppe and Neolithic ancestry.

Evaluation of saliva as a source of accurate whole-genome and microbiome sequencing data

This study evaluates saliva as a source for whole-genome and microbiome sequencing by comparing it to blood-based sequencing in 39 individuals.