BiochemistrybioRxivPreprint
Mapping the sequence determinants of constitutive activity in GPCRs
Matthew K Howard, Sara Whiteman, Patrick Rockefeller Grimes…·Willow Coyote-Maestas
The paper measures basal activity across the human GPCR family on a single scale and identifies key residues that influence constitutive signaling.
DOI 10.64898/2026.10.30.762644