Sample-efficient time-resolved X-ray crystallography with serial small wedges
Sergey S. Bukhdruker, Roman Astashkin, Dmitry Bratanov, Nicolas Caramello, Sylvain Engilberge, Christian Baeken, Taras G. Balandin, Alexander N. Popov, Antoine Royant, Christoph Mueller‐Dieckmann, Montserrat Soler‐López, Ernst Bamberg, Valentin Gordeliy, Igor Melnikov
This paper introduces a method to efficiently capture time-resolved structural changes in proteins using small crystal rotations and merging diffraction images across crystals.
bioRxiv · Oct 9, 2026 · PreprintBiophysics