Quantifying Asymmetric Coevolutionary Dynamics using Normalized Phylogenetic Costs
Sanket Wagle, Alexey Markin, Tyler J. Sherman, Christie Mayo, Tillie J. Dunham, Corey L. Brelsfoard, Lee W. Cohnstaedt, William Cody Wilson, Tavis K. Anderson, Oliver Eulenstein
The paper introduces normalized asymmetric phylogenetic costs to quantify coevolutionary dynamics, showing they capture complex relationships in virus-host systems and detect novel gene pairings in viral genomes.
bioRxiv · Jul 3, 2026 · PreprintBioinformatics