Author

Christine Guthrie

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Megan MayerleiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

1 paper

Recent·Most cited

Brr2 is a splicing fidelity factor

Megan Mayerle, Christine Guthrie

This study shows that Brr2 mutations affect splicing fidelity, leading to intron retention and altered branch-site selection, linking RP to splicing errors beyond spliceosome activation.

bioRxiv · Jun 22, 2018 · PreprintMolecular Biology