Author

Christine M. Hoffmaster

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Berit E. PowersiD· 1 shared Curt MazuriD· 1 shared Eric E. SwayzeiD· 1 shared Gemma BachmanniD· 1 shared Holly B. KordasiewicziD· 1 shared Jacqueline G. O’Rourke· 1 shared Jonathon Nguyen· 1 shared Keming Zhou· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Berit E. PowersORCID

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1 paper

Recent·Most cited

Reversable Acute Sedation Response of Phosphorothioate Antisense Oligonucleotides Following Local Delivery to the Central Nervous System

Jacqueline G. O’Rourke, Gemma Bachmann, Curt Mazur, Keming Zhou, Oleksandr Platoshyn, Mariana Bravo Hernandez, Stéphanie Klein, Jonathon Nguyen, Sebastien A. Burel, Christine M. Hoffmaster, Tom A. Zanardi, Paymaan Jafar‐Nejad, Martin Maršala, Scott P. Henry, Eric E. Swayze, , Holly B. Kordasiewicz

This study characterizes an acute sedation response caused by phosphorothioate ASOs after CNS delivery, showing it is sequence-, dose-, and chemistry-dependent and can be mitigated.

bioRxiv · Feb 13, 2025 · PreprintNeuroscience