Highly sensitive enzyme- and amplification-free, quantitative DNA detection using YVO4:Eu luminescent nanoparticle probes
Robin Kuhner, Christophe Cardone, Rafael V. Perrella, Rabei Mohammedi, Thierry Gacoin, Roxane Lestini, Cédric Bouzigues, Antigoni Alexandrou
This paper develops a sensitive, amplification-free DNA detection method using YVO4:Eu nanoparticles, achieving 50 aM sensitivity for SARS-CoV-2 n1 gene detection.
bioRxiv · Feb 25, 2026 · PreprintBioengineering