Author

Christy Lee

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Developmental Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Jingyi Jessica LiiD· 3 shared Awadalkareem Adam· 1 shared Bi‐Hung PengiD· 1 shared Brinley HarringtoniD· 1 shared Claire Julliot de La Morandière· 1 shared Dongyuan SongiD· 1 shared Elisavet IliopoulouiD· 1 shared Jing ZouiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersBioinformatics

Jingyi Jessica LiORCID

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Author profile →

4 papers

Recent·Most cited

Evolutionary dynamics of temporal transcription factor series in the insect visual brain

Konstantina Filippopoulou, Elisavet Iliopoulou, Claire Julliot de La Morandière, Christy Lee, Marina Marcet‐Houben, Toni Gabaldón, Jingyi Jessica Li, Nikolaos Konstantinides

This study reconstructs the evolutionary history of temporal transcription factor series in insect visual brains, showing conserved patterns and species-specific variations that influence neuronal diversity.

bioRxiv · Jul 8, 2026 · PreprintDevelopmental Biology

VSA-2, a novel plant-derived adjuvant for SARS-CoV-2 subunit vaccine

Awadalkareem Adam, Christy Lee, Madison C. Jones, Brinley Harrington, Jing Zou, Bi‐Hung Peng, Xuping Xie, P Wang, Tian Wang

This study develops VSA-2, a plant-derived adjuvant for SARS-CoV-2 subunit vaccines, showing it induces strong immune responses and protection comparable to QS-21.

Vaccine · Jan 22, 2026Peer-reviewedMicrobiology

Synthetic Control Enables Reliable Cluster Validation and Marker Discovery in Omics Data: From Single-Cell and Spatial to Population-Scale

Dongyuan Song, Siqi Chen, Christy Lee, Kexin Li, Xinzhou Ge, Jingyi Jessica Li

ClusterDE identifies reliable markers and validates clusters in omics data by controlling false discovery rates through synthetic control, improving accuracy in single-cell, spatial, and bulk transcriptomics.

bioRxiv · Jul 21, 2023 · PreprintBioinformatics

scDEED: a statistical method for detecting dubious 2D single-cell embeddings and optimizing t-SNE and UMAP hyperparameters

Lucy Xia, Christy Lee, Jingyi Jessica Li

scDEED detects unreliable 2D single-cell embeddings and optimizes t-SNE and UMAP hyperparameters using a reliability score across multiple scRNA-seq datasets.

bioRxiv · Apr 21, 2023 · PreprintBioinformatics