Author

Lucy Xia

Hong Kong University of Science and TechnologyORCID 0000-0002-8805-6660Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:dimensionality reduction· 1 Research Focus:GWAS / association mapping· 1 Organism:human· 1 Research Focus:imputation· 1 Assay:scRNA-seq· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Charleston W. K. ChiangiD· 1 shared Christopher A. HaimaniD· 1 shared Christy Lee· 1 shared David V. ContiiD· 1 shared Jingyi Jessica LiiD· 1 shared Jordan Li CahooniD· 1 shared Linda KachuriiD· 1 shared Xin ShengiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperGenomics

Charleston W. K. ChiangORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintApr 21, 2023

scDEED: a statistical method for detecting dubious 2D single-cell embeddings and optimizing t-SNE and UMAP hyperparameters

Lucy Xia, Christy Lee, Jingyi Jessica Li

scDEED detects unreliable 2D single-cell embeddings and optimizes t-SNE and UMAP hyperparameters using a reliability score across multiple scRNA-seq datasets.

5 citations

scRNA-seqstatistical model

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GenomicsHuman Genetics and Genomics AdvancesPeer-reviewedNov 11, 2022

Inverted genomic regions between reference genome builds in humans impact imputation accuracy and decrease the power of association testing

Xin Sheng, Lucy Y. Xia, Jordan Li Cahoon…·Charleston W. K. Chiang

The paper identifies inverted genomic regions between human reference genome builds that affect imputation accuracy and association testing power, proposing a heuristic to correct these issues.

16 citations

humanwhole-genome sequencing

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