Pan-cancer analysis of RNA binding proteins (RBPs) reveals the involvement of the core pre-mRNA splicing and translation machinery in tumorigenesis
Bin Zhang, Kamesh R. Babu, Chun You Lim, Zhi Hao Kwok, Jia Li, Siqin Zhou, Henry He Yang, Yvonne Tay
The paper analyzes RBP expression across 16 cancer types, identifies upregulated and downregulated RBPs, and links their expression to copy number and DNA methylation, suggesting roles in tumorigenesis.
bioRxiv · Jun 7, 2018 · PreprintSystems Biology