Henry He Yang

This paper shows that high-grade B cell lymphomas with MYC and BCL2 rearrangements originate from BCR-silenced follicular lymphoma cells that acquire IGL::MYC translocations, leading to resistance to CD79B-targeting therapy.

This study uses metabolically purified human hepatocytes to show that Ebola and Lassa viruses have distinct effects on liver cells.

This study shows FEZ1 is essential for human brain development by regulating neuronal progenitor subpopulations and migration, with its deletion causing abnormalities in cortical layer formation.

The paper identifies LEVER RNA as a regulator of ε-globin expression by inhibiting PRC2-mediated H3K27 methylation and disrupting promoter-LCR interactions.

This study identifies Npac as a co-factor of H3K36me3 that regulates transcriptional elongation in mouse ESCs by interacting with p-TEFb and RNA Pol II.

This study identifies ADAR1's interaction with transcriptional byproducts using integrated sequencing data, revealing its role in RNA processing and debris clearance.

The paper analyzes RBP expression across 16 cancer types, identifies upregulated and downregulated RBPs, and links their expression to copy number and DNA methylation, suggesting roles in tumorigenesis.