A benchmark of the somatic mutation landscape using single-cell and single-molecule whole-genome sequencing
Jacob E. Bridge, Chuwei Xia, Chen Zheng, Kristian Markon, Robert Frank Krueger, David Masopust, Lei Zhang, Xiao Dong
The paper benchmarks somatic mutation detection in noncancerous cells using single-cell and single-molecule whole-genome sequencing to assess platform-specific biases and their impact on mutation detection.
bioRxiv · Aug 31, 2025 · PreprintGenomics