Author

Chuxi Xiao

Tsinghua University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 3 Approach:large language model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Lei WeiiD· 3 shared Xuegong ZhangiD· 3 shared Haiyang BianiD· 2 shared Chen LiiD· 1 shared Erpai LuoiD· 1 shared Jinmeng Jia· 1 shared Minsheng HaoiD· 1 shared Qiuchen MengiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBioinformatics

Lei WeiORCID

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3 papers

Recent·Most cited

Tokenizing single-cell transcriptomes as a native language for large language models

Chuxi Xiao, Yuang Ding, Haiyang Bian, Yixin Chen, Lei Wei, Xuegong Zhang

This paper introduces CellTok, a method to convert single-cell transcriptomes into tokens for LLMs, enabling joint processing of cellular data and text.

bioRxiv · Oct 22, 2025 · PreprintBioinformatics

Toward mastering the cell language by learning to generate

Yixin Chen, Haiyang Bian, Lei Wei, Jinmeng Jia, Xiaomin Dong, Yuzhuo Li, Yubo Zhao, Xinze Wu, Chen Li, Erpai Luo, Chuxi Xiao, Minsheng Hao, Xuegong Zhang

The paper introduces scMulan, a large AI model trained to generate cell transcriptomics data with specific attributes, showing it can generate pseudo data, predict missing attributes, and identify driving regulators.

bioRxiv · Jan 25, 2024 · PreprintBioinformatics

Benchmarking multi-omics integration algorithms across single-cell RNA and ATAC data

Chuxi Xiao, Yixin Chen, Qiuchen Meng, Lei Wei, Xuegong Zhang

This study benchmarks 12 multi-omics integration methods on scRNA-seq and scATAC-seq data across three tasks, identifying method-specific strengths and providing selection guidelines.

Briefings in Bioinformatics · Jan 22, 2024Peer-reviewedBioinformatics