Author

Clémence Gruget

Massachusetts Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biophysics· 1

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Approach:biophysical modeling· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

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Bharat G. ReddyiD· 1 shared Jonathan M. MooreiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiophysics

Bharat G. ReddyORCID

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1 paper

Recent·Most cited

BiophysicsCommunications BiologyPeer-reviewedApr 7, 2025

A structural and mechanistic model for BSEP dysfunction in PFIC2 cholestatic disease

Clémence Gruget, Bharat G. Reddy, Jonathan M. Moore

This study investigates how BSEP mutations cause PFIC2 by analyzing protein stability and structure, identifying a key interface affected by disease-causing variants.

6 citations

humanstructural biology

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