Morphine causes distinct changes in the lipidome throughout the brain and body after acute or chronic administration: implications for novel endogenous lipid signaling systems involved in opioid reward and withdrawal
Taylor J. Woodward, Elyse Chafee, Evan Cannon, Clarissa Schmitt, Ken Mackie, Heather B. Bradshaw
This study examines how morphine alters lipid levels in different brain and body regions after acute or chronic administration, identifying potential endogenous lipid signaling systems involved in opioid reward and withdrawal.
bioRxiv · Sep 23, 2026 · PreprintNeuroscience