Allosteric regulation of Glutamate dehydrogenase deamination activity
Soumen Bera, Mubasher Rashid, Alexander B. Medvinsky, Gui‐Quan Sun, Bai-Lian Li, Claudia Acquisti, Adnan Sljoka, Amit Chakraborty
This study identifies NADH as a positive allosteric modulator of GDH, revealing structural changes that inhibit deamination activity through conformational rearrangements.
Scientific Reports · Oct 5, 2020Peer-reviewedSystems Biology