Mapping the endothelial O-GlcNAcome uncovers CCAR1 as a regulator of senescence
Andreas Will, Regine Heller, Claudia Ender, Felix R. Schneidmadel, Florian Meier-Rosar, Darya Zibrova
This study identifies CCAR1 as an O-GlcNAc substrate that regulates endothelial senescence by modulating apoptosis and DNA damage response.
bioRxiv · Feb 14, 2026 · PreprintBiochemistry