Regine Heller

Acetylation-dependent remodeling of the secretory pathway shapes the senescence-associated secretome

This study identifies acetylation-dependent remodeling of the secretory pathway in senescence, showing its role in shaping the senescence-associated secretome.

Mapping the endothelial O-GlcNAcome uncovers CCAR1 as a regulator of senescence

This study identifies CCAR1 as an O-GlcNAc substrate that regulates endothelial senescence by modulating apoptosis and DNA damage response.

Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis

This study identifies polyamines as key regulators of epithelial regeneration in aged intestines, showing they enhance protein homeostasis and restore regenerative capacity through dietary manipulation.

NanTex enables computational multiplexing and phenotyping of organelles across super-resolution modalities

NanTex enables multiplexing and phenotyping of organelles using nanotexture descriptors from single-channel super-resolution microscopy data across multiple modalities.