Author

Claus Wilke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:differential expression· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Colin W. Brown· 1 shared Daniel R. BoutziD· 1 shared Edward M. MarcotteiD· 1 shared Jeffrey E. BarrickiD· 1 shared Julian Echave· 1 shared Maria D. Person· 1 shared Viswanadham SridharaiD· 1 shared

Activity by Year

2016-2017 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

Colin W. Brown

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Large-scale analysis of post-translational modifications in E. coli under glucose-limiting conditions

Colin W. Brown, Viswanadham Sridhara, Daniel R. Boutz, Maria D. Person, Edward M. Marcotte, Jeffrey E. Barrick, Claus Wilke

The paper analyzes PTMs in E. coli under glucose-limiting conditions, identifying novel targets and temporal patterns for specific modifications and suggesting a new biological function for N-terminal acetylation.

BMC Genomics · Apr 17, 2017Peer-reviewedMicrobiology

Biophysical models of protein evolution: Understanding the patterns of evolutionary sequence divergence

Julian Echave, Claus Wilke

This paper reviews biophysical models of protein evolution, showing that slow evolution is linked to selection against toxic misfolding and misinteractions, and that slowly evolving sites often impact structure and stability rather than function.

bioRxiv · Aug 30, 2016Biophysics