Daniel R. Boutz

This study shows that imprinted antibody lineages can persist for over 50 years and dominate cross-neutralizing recall responses to poliovirus.

This study evolves a T7 RNA polymerase variant with a capping enzyme to enable efficient gene expression in eukaryotes, showing improved performance in yeast and mammalian cells.

The paper systematically profiles protein dynamics in ale yeast during fermentation and repitching, identifying changes in ergosterol and isobutyraldehyde metabolism.

The paper analyzes proteomic changes in Arabidopsis hybrids and allotetraploids, finding nonadditive protein expression and increased solubility of photosynthetic proteins associated with hybrid vigor.

This study engineers yeast to produce cholesterol, enabling functional expression of human opioid and other GPCRs, creating biosensors with measurable agonist responses and antagonist inhibition.

The paper identifies SARS-CoV-2 neutralizing antibodies from convalescent patients and describes a novel quaternary binding mechanism using high-throughput methods.

The paper sequences 320 SARS-CoV-2 genomes from Houston to study early pandemic spread, finding diverse origins and no evidence of more virulent strains.

This study shows that transcript degradation and codon usage regulate gene expression in bacteriophage T7 through a dynamic interplay between transcription, translation, and transcript degradation.

The paper investigates how codon deoptimization in bacteriophage T7 reduces protein expression and viral fitness by halving translation of key genes.

This study presents a comprehensive transcriptomics and proteomics dataset of E. coli under 34 growth conditions, revealing differences between exponential and stationary phases and differential gene expression under specific stresses.

The paper analyzes PTMs in E. coli under glucose-limiting conditions, identifying novel targets and temporal patterns for specific modifications and suggesting a new biological function for N-terminal acetylation.