Impaired learning and memory ability induced by a bilaterally hippocampal injection of streptozotocin in mice: involved with the adaptive changes of synaptic plasticity
Congcong Qi, Xing-Xing Chen, Xinran Gao, Jingxian Xu, Sen Liu, Jin‐Fang Ge
This study establishes an AD mouse model using bilateral hippocampal STZ injection, showing impaired learning/memory and altered synaptic plasticity with changes in protein expression and inflammatory response.
Frontiers in Aging Neuroscience · Mar 1, 2021Peer-reviewedNeuroscience