Pushing the Isotopic Envelope: When carrier channels pollute their neighbors signals
Connor Peterson, Hannah Boekweg, Eilenora Presley, Samuel Payne
The paper investigates how impurities in isobaric labeling reagents can cause contamination in single-cell proteomics, leading to inaccurate quantification when carrier channels are overused.
bioRxiv · Apr 15, 2024 · PreprintBioinformatics