Spatial dissection of ADC/RPT targets defines therapeutic opportunities inrhabdoid tumors
Nic Gabriel Reitsam, Victoria E. Fincke, Maria Daniela Hernandez Ramirez, Marlena Mucha, Éva Sipos, Lisa Siebenhüter, Johanna S. Enke, Maurice Loßner, Christian Vokuhl, Constantin Lapa, Martin Hasselblatt, Michael Frühwald, Bruno Märkl, Pascal David Johann
The paper identifies surface protein targets for ADC and RPT in rhabdoid tumors through transcriptomic and spatial analysis, revealing subgroup-specific expression patterns.
bioRxiv · Dec 13, 2025 · PreprintCancer Biology