Low fidelity DNA polymerase IV accelerates genome evolution in Pseudomonas aeruginosa
Sofía Daiana Castell, Consuelo M. Fernandez, Ignacio N. Tumas, Lucía Malvina Margara, María Clara Miserendino, Danilo G. Ceschin, Roberto J. Pezza, Mariela Roxana Monti
This study investigates the mutagenic effects of DNA polymerase IV in Pseudomonas aeruginosa, showing it drives genome evolution through specific mutation patterns and impacts virulence-related genes.
bioRxiv · Oct 22, 2024 · PreprintGenomics