Roberto J. Pezza

This study identifies ZCWPW1 as a chromatin-based regulator of telomere architecture and meiotic chromosome movements, independent of PRDM9.

This study identifies a CHD4-CTCF regulatory axis that controls key developmental programs and transitions in male germ cells by regulating chromatin structure and gene expression.

This study identifies KIF5B as a key component of the force-generating machinery for meiotic chromosome movements, interacting with the KASH5-LINC complex.

This study investigates the mutagenic effects of DNA polymerase IV in Pseudomonas aeruginosa, showing it drives genome evolution through specific mutation patterns and impacts virulence-related genes.

The paper describes a method to efficiently isolate synchronized mouse spermatocytes for genome-wide chromatin analysis, demonstrating its use in ChIP-seq studies of meiotic chromatin binding sites.

This study shows that CHD4 is essential for neonatal spermatogonia survival and gonad development by regulating Dmrt1 and Plzf expression.

This paper shows that shugoshin protects centromeric synaptonemal complex components and promotes proper segregation of non-crossover partner chromosomes in meiosis.

This study shows that PSMC3 is essential for spermatogonia niche establishment in mouse gametogenesis, leading to impaired gonad development and fertility.

The paper shows that heterochromatin maintains centromere associations in mouse spermatocytes when crossovers are absent.

The paper shows that SUMO and ubiquitin-proteasome systems regulate meiotic prophase events in mouse by controlling protein turnover through RNF212 and HEI10.