Molecular BiologyPLoS PathogensPeer-reviewed
High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanisms
Manja Czech‐Sioli, Thomas Günther, Marlin Therre…·Nicole Fischer
This study identifies two MCPyV integration patterns in MCC and links them to NHEJ and MMBIR mechanisms, showing integration preference for open chromatin and viral promoter-driven oncogene expression.
44 citations