Transcriptional regulatory logic of the diurnal cycle in the mouse liver
Jonathan Aryeh Sobel, Irina Krier, Teemu Andersin, Sunil Raghav, Donatella Canella, Federica Gilardi, Alexandra Styliani Kalantzi, Guillaume Rey, Benjamin Weger, Frederic Gachon, Matteo Dal Peraro, Nouria Hernandez, Ueli Schibler, Bart Deplancke, Felix Naef, CycliX consortium
This study maps DNase I hypersensitive sites in mouse liver during the diurnal cycle to uncover the transcriptional regulatory logic of diurnal rhythms, revealing the role of CLOCK:BMAL1 complexes and feeding-fasting signals.
bioRxiv · Sep 27, 2016Genomics