Evaluation of an optimized protocol and Illumina ARTIC V4 primer pool for sequencing of SARS-CoV-2 using COVIDSeq™ and DRAGEN™ COVID Lineage App workflow
Cyndi Clark, Matthew T. Hardison, Holly Houdeshell, Alec Vest, Darcy A. Whitlock, Dylan Skola, Jeff Koble, Michael Oberholzer, Gary P. Schroth
The paper compares two SARS-CoV-2 sequencing primer pools, finding that the ARTIC V4 pool performs better, especially in low viral load samples.
bioRxiv · Jan 7, 2022 · PreprintGenomics