Antigen structure affects cellular routing through DC-SIGN
C. Jarvis, D. B. Zwick, J. C. Grim, L. R. Prost, M. M. Alam, J. Gardiner, S. Park, L. L. Zimdars, N. M. Sherer, L. Kiessling
This study shows that antigen structure influences DC-SIGN-mediated uptake and trafficking, with larger particulate antigens being routed to HIV-1-associated compartments.
bioRxiv · Mar 4, 2019Immunology