Thermodynamic genome-scale metabolic modeling of metallodrug resistance in colorectal cancer
H. A. Herrmann, M. Rusz, D. Baier, M. A. Jakupec, B. K. Keppler, W. Berger, G. Koellensperger, J. Zanghellini
The paper uses metabolomics and metabolic modeling to compare drug-sensitive and -resistant colorectal cancer cells, highlighting the importance of normalization in identifying drug-specific metabolic changes.
bioRxiv · Jun 9, 2021Cancer Biology